Danse-thérapie et Parkinson

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Electrogastrographyc activity in Parkinson's disease patients with and without motor fluctuations

Identifieur interne : 000228 ( Main/Exploration ); précédent : 000227; suivant : 000229

Electrogastrographyc activity in Parkinson's disease patients with and without motor fluctuations

Auteurs : Giovanni Albani [Italie] ; Nadia El Assawy [Italie] ; Stefania Cattaldo [Italie] ; Marilena De Gennaro [Italie] ; Francesca Gregorini [Italie] ; Luca Pradotto [Italie] ; Alessandro Mauro [Italie]

Source :

RBID : ISTEX:8DC8C7D43A957EF02E2C29A6ED1912382B0F8A5D

English descriptors

Abstract

Gastroenteric dysfunctions are very common in Parkinson's disease, but their relationship with dopaminergic response and motor fluctuations is still unclear. Electrogastrography is a noninvasive method for measuring gastric myoelectrical activity.
We evaluated the effects of levodopa intake on the motility of empty stomachs in Parkinson's disease patients with and without motor fluctuations.
The electrogastrography findings showed a normal pattern not influenced by levodopa intake, unrelated to plasmatic levodopa concentrations and to clinical parameters.
Our results suggest that at rest gastric activity of Parkinson's disease patients is normal and plasmatic levodopa variability is not influenced by gastric motility. © 2011 Movement Disorder Society

Url:
DOI: 10.1002/mds.23662


Affiliations:


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<div type="abstract">Gastroenteric dysfunctions are very common in Parkinson's disease, but their relationship with dopaminergic response and motor fluctuations is still unclear. Electrogastrography is a noninvasive method for measuring gastric myoelectrical activity.</div>
<div type="abstract">We evaluated the effects of levodopa intake on the motility of empty stomachs in Parkinson's disease patients with and without motor fluctuations.</div>
<div type="abstract">The electrogastrography findings showed a normal pattern not influenced by levodopa intake, unrelated to plasmatic levodopa concentrations and to clinical parameters.</div>
<div type="abstract">Our results suggest that at rest gastric activity of Parkinson's disease patients is normal and plasmatic levodopa variability is not influenced by gastric motility. © 2011 Movement Disorder Society</div>
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